Early screening for preeclampsia
نویسندگان
چکیده
منابع مشابه
A competing risks model in early screening for preeclampsia.
OBJECTIVE It was the aim of this study to develop models for the prediction of preeclampsia (PE) based on maternal characteristics and biophysical markers at 11-13 weeks' gestation in which gestation at the time of delivery for PE is treated as a continuous variable. METHODS This was a screening study of singleton pregnancies at 11-13 weeks including 1,426 (2.4%) cases that subsequently devel...
متن کاملMicroarray screening for novel preeclampsia biomarker candidates.
INTRODUCTION Our aim was to identify novel biomarker candidates for the near-term prediction of preeclampsia in a homogenous collective. In this study, we screened at the genome-wide level for gene expression in placental villous tissue from patients with severe preeclampsia in comparison to normal healthy pregnancies. MATERIAL AND METHODS Total RNA was extracted from placental villous tissue...
متن کاملScreening for preeclampsia pathogenesis related genes.
OBJECTIVES Preeclampsia is a complication of pregnancy that severely threatens the health of the mother and infant, yet the mechanism of pathogenesis remains unclear. In this article, gene array technology was applied to identify the genes related to the pathogenesis of preeclampsia, and to explore the regulatory effect of epigenetic modification by on these genes. PATIENTS AND METHODS Placen...
متن کاملScreening models using multiple markers for early detection of late-onset preeclampsia in low-risk pregnancy
BACKGROUND Our primary objective was to establish a cutoff value for the soluble fms-like tyrosine kinase 1(sFlt-1)/placental growth factor (PlGF) ratio measured using the Elecsys assay to predict late-onset preeclampsia in low-risk pregnancies. Our secondary objective was to evaluate the ability of combination models using Elecsys data, second trimester uterine artery (UtA) Doppler ultrasonogr...
متن کاملEarly Prediction of Preeclampsia
Effective screening for the development of early onset preeclampsia (PE) can be provided in the first-trimester of pregnancy. Screening by a combination of maternal risk factors, uterine artery Doppler, mean arterial pressure, maternal serum pregnancy-associated plasma protein-A, and placental growth factor can identify about 95% of cases of early onset PE for a false-positive rate of 10%.
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ژورنال
عنوان ژورنال: Revista Brasileira de Ginecologia e Obstetrícia
سال: 2011
ISSN: 0100-7203
DOI: 10.1590/s0100-72032011001100008